IMMUNOLOGY

IMMUNOLOGY Question Papers (Supple, 2008)

SET :1

1. What is meant by immunity and explain about the various components involved in the immune system. [4+12]
2. Explain about gene regulation in anti body production. [16]
3. Write a short notes on: [8+8]
(a) congenic.
(b) MHC class I
(c) MHC class II
(d) MHC class III
4. What a short notes on: [8+8]
(a) interferons.
(b) interlevkines.
(c) Tc cells.
(d) TH cells.
5. Define hybridoma and explain monoclonal antibody production? [3+13]
6. Discuss ELISA in detail along with its applications? [16]
7. Give an account on type I hypersensitivity? [16]
8. Define autoimmunity and explain with suitable examples? [8+8]


SET :2

1. How the various types of immune cells are originated. [16]
2. Define antibody and describe about their structure in detail with a neat diagram? [12+4]
3. Explain about the MHC and what is their role in Humoral and cellular immunity. [5+11]
4. (a) What Macrophages and what is its role in cell mediated immunity. [8+8]
(b) What are langerhance cells and what is its role in cell mediated immunity.
5. Define hybridoma and explain monoclonal antibody production? [3+13]
6. Explain the process of TH cell activation in detail? [16]
7. Explain type II hypersensitivity with examples? [16]
8. Describe different types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]


SET :3

1. (a) What are adjuvants and what is their contribution to immunogenicity. [2+6]
(b) Explain about the antigenicity and antigenic determinants. [4+4]
2. Define immunoglobulin and explain about its structure and function. [3+8+5]
3. What are monoclonal antibodies and explain its importance? [12+4]
4. What are interferons and explain about various types of cytokines . [8+8]
5. Define hybridoma and explain monoclonal antibody production? [3+13]
6. Explain different types of forces that causes antigen - antibody interactions? [16]
7. Explain the blood transfusion mechanism in detail? [16]
8. Define immunotoxins & explain their roles in terms of therapy? [8+8]


SET :4

1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13]
2. Explain about gene regulation in anti body production. [16]
3. What are monoclonal antibodies and explain its importance? [12+4]
4. (a) What Macrophages and what is its role in cell mediated immunity. [8+8]
(b) What are langerhance cells and what is its role in cell mediated immunity.
5. (a) Explain the process for enrichment of Hematopoietic stem cells? [8+8]
(b) Give an account on the clinical applications of stem cells?
6. (a) Give an account on the properties of cytokines? [8+8]
(b) Discuss the functions of cytokines in detail?
7. Give an account on type I hypersensitivity? [16]
8. Describe different types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]
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LABELS: IMMUNOLOGY (IMM)
IMMUNOLOGY Question Papers (Regular, 2008)
POSTED BY M.S.CHOWDARY AT 7:38 AM
SET :1

1. What is the difference between immunogen and antigen? Name the factors and explain how they influence the immunogenecity?
2. What is haematopoiesis? Describe the pathways and cells which originate from haematopoiesis. [16]
3. Explain in detail about the structure and function of mucosl associated lymphoid tissue. [16]
4. What is systemic defense (SD)? Name the cells in the blood which contribute to SD and their function. [16]
5. Give the schematic presentation of signal transduction pathways through which B Cell get activated. [16]
6. Compare and differentiate TCR with mIG molecule. [8+8]
7. Discuss the treatment modalities for controlling the Type I Hypersensitivity reactions. [16]
8. Discuss the Systemic autoimmune disorders with suitable examples. [16]


SET :2

1. Write short notes on the following:
(a) Passive immunization
(b) Active immunization
(c) Haptens
(d) Adjuvants.
2. Write in brief about the structure and function of the following:
(a) Macrophages
(b) Mast cells
(c) T-cells
(d) Natural killer cells. [4+4+4+4]
3. What are the differences between primary and secondary organs? Explain in short about the structure and function of bone marrow and spleen. [16]
4. What is systemic defense (SD)? Name the cells in the blood which contribute to SD and their function. [16]
5. Give the schematic presentation of signal transduction pathways through which B Cell get activated. [16]
6. Discuss how the MHC is involved in disease susceptibility. [16]
7. Discuss the mechanism of Chemilumniscence and its applications in clinical diagnosis. [16]
8. Write short notes on:
(a) Acute rejection
(b) TUMOR INFILTRATING LYMPHOCYTES
(c) Sequestered organs
(d) Lymphorcine-activated KillerCells. [4+4+4+4]


SET :3

1. What is innate immunity? Write about the cells involved and their role in innate immunity?
2. What is haematopoiesis? Describe the pathways and cells which originate from haematopoiesis. [16]
3. Explain in detail about the structure and function of mucosl associated lymphoid tissue. [16]
4. What is systemic defense (SD)? Name the cells in the blood which contribute to SD and their function. [16]
5. Write short notes on:
(a) Applications of abzymes
(b) Clinical uses of Monoclonal antibodies
(c) HAT Medium. [5+5+6]
6. Compare and differentiate TCR with mIG molecule. [8+8]
7. Discuss various types of ELISA. [16]
8. What is immunological tolerance? How is tolerance is crucial for prevention of autoimmune disorders? [16]


SET :4

1. What is acquired immunity? Write about the cells involved and their role in acquired immunity?
2. Write in short different cells of immune system and their mode of action. [16]
3. What are the differences between primary and secondary organs? Explain in short about the structure and function of bone marrow and spleen. [16]
4. What is systemic defense (SD)? Name the cells in the blood which contribute to SD and their function. [16]
5. Explain the signal transduction pathways through which B Cell get activated.[16]
6. Discuss how endogenous antigens processed & presented through MHC. [16]
7. Explain the various Ag-Ab reactions that are used in clinical diagnosis. [16]
8. What are generalized and specific immunotherapies? [16]
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LABELS: IMMUNOLOGY (IMM)
IMMUNOLOGY Question Papers (Supple, 2007)
POSTED BY M.S.CHOWDARY AT 7:24 AM
SET : 1
1. a)What is meant by innate immunity and explain about its importance in newly born baby.
b)Explain about the acquired immunity.
2. a)What is meant by humoral immunity and what are the components involved in it.
b)What are different T cell antigen receptors and list their functions.
3. What are monoclonal antibodies and explain its importance?
4. What is meant by cell mediated immunity and explain about the different components involved in it.
5. Define hybridoma and explain monoclonal antibody production?
6. Explain flow cytometry and discuss its role in antigen - antibody interactions?
7. Discuss the consequences and regulation of type I hypersensitivity?
8. Define tumor antigens and give their significance in immunology?
SET : 2
1. What is meant by immunity and explain about the various components involved in the immune system.
2. Discuss about the different classes of immunoglobulin and explain about their role in immunity.
3. Write a short notes on :
a) Congenic
b) MHC class I
c) MHC class II
d) MHC class III
4. What macrophages and what is its role in cell mediated immunity. What are langerhan cells and what is its role in cell mediated immunity.
5. Explain the process of formation and selection of hybrid cells?
6. Explain different types of antigen – antibody interactions?
7. Discuss about the purified macromolecules as vaccines?
8. Describe the cancer theraohy in detail?
SET : 3
1. What is meant by immunity and explain about the various components involved in the immune system.
2. Define antibody and describe about their structure in detail with a neat diagram?
3. What are monoclonal antibodies and explain its importance?
4. What are interferons and explain about various types of cytokines.
5. Explain about immunosupression in detail along with an example.
6. Explain different types of antigen – antibody interactions?
7. Give an account on type I hypersensitivity?
8. Give an account on the functional classification of cancer – associated genes?
SET : 4
1. What is meant by hematopoesis and explain its role in the generation of various immune cells.
2. Discuss about the B cell mediated immunity and explain about the basic structure of immunoglobulin.
3. What are monoclonal antibodies and explain its importance?
4. Discuss about various types of cell mediator defence mechanism.
5. Define hybridoma and explain monoclonal antibody production?
6. Explain different types of forces that causes antigen – antibody interactions?
7. Discuss the consequences and regulation of type I hypersensitivity?
8. Explain the mechanisms of immunity to tumor antigens?
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LABELS: IMMUNOLOGY (IMM)
IMMUNOLOGY Question Papers (Supple, 2006)
POSTED BY M.S.CHOWDARY AT 7:23 AM
SET :1

1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13]

2. Define immunoglobulin and explain about its structure and function. [3+8+5]

3. (a) Describe in brief about the Human MHC class I genes and explain about their functions. [4+4]
(b) Describe in brief about Human MHC class II genes and explain about their role. [4+4]

4. Discuss about various types of cell mediator defense mechanism. [16]

5. Define hybridoma and explain monoclonal antibody production? [3+13]

6. Define affinity and determine antibody affinity by equilibrium dialysis method? [2+14]

7. Give an account on the mediators of type I hypersensitivity? [16]

8. Describe different types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

SET : 2

1. Explain any two [8+8]
(a) adjuvants.
(b) complement.
(c) MHC.
(d) T cells.

2. Define immunoglobulin and explain about its structure and function. [3+8+5]

3. What are monoclonal antibodies and explain its importance? [12+4]

4. What is meant by cell mediated immunity and explain about the different components involved in it. [8+8]

5. Define cellular immunity and explain the process involved in identification of cell types of immune system? [4+12]

6. Explain flow Cytometry and discuss its role in antigen - antibody interactions? [4+12]

7. Describe the various types of type III hypersensitivity? [16]

8. Explain the significance of MHCs in graft rejection? [16]

SET :3

1. What is meant by immunity and explain about the various components involved in the immune system. [4+12]

2. Give an account on basic structure of B cells and explain their activation process. [5+11]

3. What is meant by Idiotypic antibodies and explain their role. [11+5]

4. What is meant by phagocytosis and what is its role in the cell mediated immunity. [8+8]

5. Define hybridoma and explain monoclonal antibody production? [3+13]

6. Explain the role of cytokines in signal transduction? [16]

7. The DNA vaccines are proved to be highly beneficial. Justify? [16]

8. Describe different types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

SET :4

1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13]

2. Explain the process involved in the activation of B cells. [16]

3. What are monoclonal antibodies and explain its importance? [12+4]

4. Explain various types of cells involved in the cell mediated immunity. [16]

5. Explain the process of formation and selection of hybrid cells? [10+6]

6. Explain the role of cytokines in signal transduction? [16]

7. Give an account on the significance of vaccination in Immunology? [16]

8. Describe different types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]
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LABELS: IMMUNOLOGY (IMM)
IMMUNOLOGY Question Papers (Regular, 2005)
POSTED BY M.S.CHOWDARY AT 7:22 AM
SET :1

1. What are the various cells involved in the immune response and explain about their role in immune response.

2. Define immunoglobulin and explain about its structure and function.

3. Write a short notes on:
(a) Haplotypes
(b) HLA genes
(c) H-2 genes
(d) Polygenic

4. (a) What Macrophages and what is its role in cell mediated immunity.
(b) What are langerhance cells and what is its role in cell mediated immunity.

5. Describe the differences between general and specific immunosuppressive therapies?

6. Explain different types of antigen-antibody interactions?

7. Explain the blood transfusion mechanism in detail?

8. Give an account on the significance of autoimmunity in Immunology?

SET :2

1. Explain any two
(a) adjuvants
(b) complement
(c) MHC
(d) T cells

2. Define immunoglobulin and explain about its structure and function.

3. What are monoclonal antibodies and explain its importance ?

4. What is meant by cell mediated immunity and explain about the different components involved in it.

5. Give an account on immunosuppressive therapy?

6. (a) Give an account on the properties of cytokines?
(b) Discuss the functions of cytokines in detail?

7. Give an account on type I hypersensitivity?

8. Define autoimmunity and explain with suitable examples?

SET :3

1. Explain any two
(a) adjuvants
(b) complement
(c) MHC
(d) T cells

2. Write a short notes on :
(a) IgG
(b) IgA
(c) VH regions
(d) Antibody valence

3. (a) Name the test which is employed in detection of typhoid fever.
(b) Explain in brief the different types of Ag-Ab interactions?

4. Discuss about various types of cell mediator defense mechanism.

5. Explain the significance of stem cells in Immunology and their role in transplantation stem cells and explain their role in transplantation?

6. Explain different types of antigen-antibody interactions?

7. Define active immunization & describe the process for designing vaccines for active immunization?

8. Give an account on the significance of autoimmunity in Immunology?

SET :4

1. What are the various organs involved in the immune system.

2. Explain about gene regulation in anti body production

3. (a) Describe in brief about the Human MHC class I genes and explain about their functions.
(b) Describe in brief about Human MHC class II genes and explain about their role

4. What are interferons and explain about various types of cytokines.

5. Define hybridoma and explain monoclonal antibody production?

6. Explain different types of antigen-antibody interactions?

7. Explain the TDTH -mediated hypersensitivity in detail?

8. Give an account on the significance of autoimmunity in Immunology?
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LABELS: IMMUNOLOGY (IMM)
IMMUNOLOGY Question Papers (Supple, 2005)
POSTED BY M.S.CHOWDARY AT 7:22 AM
SET :1

1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13]

2. Write a short notes on :(a) antigen receptors. [8+8]
(b) VL regions.
(c) VH regions.
(d) Hinge region.
3. What are monoclonal antibodies and explain its importance ? [12+4]

4. Explain the process of regulation cell mediated immunity and what is the role of cytokines in it. [8+8]

5. (a) Define HAT medium and explain its role in hybridoma technology? [2+6]
(b) Give an account on the advantages of hybridoma technology? [8]

6. (a) Give an account on the properties of cytokines? [8+8]
(b) Discuss the functions of cytokines in detail?

7. Give an account on type I hypersensitivity? [16]

8. Give an account on the significance of autoimmunity in Immunology? [16]

SET :2

1. What is meant by complement and explain in detail the different pathways of complement system? [3+13]

2. Discuss about the B cell mediated immunity and explain about the basic structure of Immunoglobulin. [8+8]

3. What is meant by Idiotypic antibodies and explain their role. [11+5]

4. (a) What Macrophages and what is its role in cell mediated immunity. [8+8]
(b) What are langerhance cells and what is its role in cell mediated immunity.

5. Explain the process of formation and selection of hybrid cells? [10+6]

6. Explain different types of antigen-antibody interactions? [16]

7. Define vaccine and describes different types of vaccines? [2+14]

8. Describe different types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

SET :3

1. What is meant by immunity and explain about the various components involved in the immune system. [4+12]

2. Discuss about the different classes of immunoglobulin and explain about their role in Immunity. [8+8]

3. What are monoclonal antibodies and explain its importance ? [12+4]

4. What is meant by cell mediated cytotoxicity and explain about role in immune response. [8+8]

5. Explain the process of formation and selection of hybrid cells? [10+6]

6. (a) Give an account on the properties of cytokines? [8+8]
(b) Discuss the functions of cytokines in detail?

7. Give an account on Immune complex-mediated hypersensitivity? [16]

8. Explain different animal models for autoimmune diseases? [16]

SET :4

1. (a) What is meant by innate immunity and explain about its importance in newly born baby. [3+5+8]
(b) Explain about the acquired immunity.

2. Explain about gene regulation in anti body production. [16]

3. (a) What is the diagnostic method of shigella and list out the other applications of it? [5+3]
(b) Explain the diagnostic method of diphtheria and list its other applications.[5+3]

4. What is meant by cell mediated immunity and explain about the different components involved in it. [8+8]

5. Explain about immunosuppression in detail along with an example. [12+4]

6. Explain different types of forces that causes antigen - antibody interactions? [16]

7. Discuss the consequences and regulation of type I hypersensitivity? [16]

8. Give an account on the significance of autoimmunity in Immunology? [16]