CELL BIOLOGY

Code No: 43111 Set No. 1
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. What is the general organization of a prokaryotic cell and explain functions of each
organalle or structure with in it. [16]
2. Write a brief account on :
(a) Cilia
(b) Flagella. [8+8]
3. Which organelle is called as the “power house of the cell”. Explain why? [16]
4. Explain the differences between active and passive transport giving suitable exam-
ples. [16]
5. (a) What are FtsZ proteins?
(b) Explain their role in the Binary fission in prokaryotes? [6+10]
6. (a) What are embryonic stem cells?Why are these cells called as totipotent cells?
(b) Explain the role of embryonic stem cells in repairing the defective tissues.
[8+8]
7. Describe the different kinds of intercellular signaling strategies Give a suitable ex-
ample for each strategy. [16]
8. Explain with an experimental strategy how transgenic mice can be used as a model
to uncover the function of cancer critical genes? [16]
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Code No: 43111 Set No. 2
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. Classify the cells based on cell complexity with respect to cell size, shape and
components. [16]
2. Write a short note on:
(a) Integral proteins
(b) Phospholipids
(c) Peripheral proteins
(d) Actin. [4×4]
3. Write about the organelle which can synthesise food material from Sunlight. [16]
4. Explain the differences between endocytosis and exocytosis and discuss their sig-
nificance in the cellular activity. [16]
5. (a) Explain the role of Mitogens in stimulating the cell division?
(b) What is the role of Growth factors and survival factors during cell division?
[10+6]
6. Explain with at least one suitable example that homologous proteins that play a
role in animal development function interchangeably in mice and flies? [16]
7. (a) What is action potential?
(b) Explain the mechanism, how electrical impulses lead to secretion of neuro-
transmitter? [4+12]
8. (a) Explain how microarray strategy could be used in detection of genes involved
in cancer progression?
(b) Name at least one gene that was identified by this approach in highly metasta-
tic cells? [13+3]
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Code No: 43111 Set No. 3
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. Name few instruments that are used to observe different types of cells. Which
instrument is now widely used to observe tiny cells. Give shapes of few existing
cells. [16]
2. Describe the role of microfilaments in cell motility. [16]
3. One organelle in the Eukaryotic cell has evolved from a prokaryotic cell that gained
entry by ‘endosymbiotic process’- Name the organelle and write about its functions.
[16]
4. Write about the methods of transport process driven by ATP. [16]
5. Explain how cell cycle control system depends on cyclical proteolysis? What is the
role of Ubiquitin in this process? [16]
6. Explain how changing patterns of cell adhesion molecules force cells into new
arrangement? [16]
7. “Different cells respond differently to the same extracellular signal molecule”- com-
ment on this statement with particular reference to the action of acetyl choline
signaling molecule. [16]
8. Explain how in a population of telomere deficient cells, the loss of p53 facilitates
the development of cancer? [16]
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Code No: 43111 Set No. 4
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. Write in detail about the different functions of cells in the body. [16]
2. Briefly discuss the different types of intermediate filaments and their role in a cell.
[16]
3. Write short notes on
(a) Photosystem- II
(b) Chemi-osmotic theory
(c) Nuclear pore complex
(d) Chlorophyll. [4×4]
4. What is simple diffusion? Explain how it differs from active transport. [16]
5. Name the two cytoskeletal machines that operates in M-phase that ensures Mitosis
always precedes cytokinesis? [16]
6. Explain with at least one suitable example that homologous proteins that play a
role in animal development function interchangeably in mice and flies? [16]
7. Explain how signaling by phosphorylation and signaling by GTP-binding protein
acts as molecular switches in intra cellular signaling proteins? [16]
8. Explain in detail what is genetic instability? Explain the mechanism involved in
cancer cells that lead to genetically instability? [16]
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CELL BIOLOGY-may supply 2009
Code No: 33111 Set No. 1
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. Describe the structure of a generalized prokaryotic cell. Indicate the ways in which
a prokaryotic cell would differ in structure from the generalized eukaryotic cell. [16]
2. What are microtubules structurally and functionally? [16]
3. What are cell organelles? Why are mitochondria important for the functioning of
eukaryotic cells? [16]
4. What are Lysosomal & Vacuolar membrane pumps? [16]
5. During which phase of mitosis do the nucleolus and the nuclear membrane break
down and disappear? Describe the roles that the spindle fibers play in mitosis.
[16]
6. Q14. Write short notes on:
(a) Pattern of stem cell division
(b) Different types of stem cells. [8+8]
7. How are receptors involved in cellular regulation? [16]
8. Citing a suitable example, explain the role of cAMP as secondary messenger in
hormone action. [16]
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Code No: 33111 Set No. 2
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. Compare and contrast the properties and strategies of eukaryotic and prokaryotic
cells in terms of cell size, compartmentalization, nuclei, internal membranes, DNA
and cell specialization. [16]
2. Discuss the major components of plasma membrane. [16]
3. Discuss each of the following:
(a) the structure and role of the cell membrane
(b) the structure and role of mitochondria. [16]
4. What is the difference between simple diffusion and Fasciliated diffusion? [16]
5. Give an overview of the major events taking place in a typical eukaryotic cell cycle.
[16]
6. With respect to cell differentiation write notes on:
(a) Cytoplasmic determinants
(b) Nucleoplasmic interactions. [8+8]
7. Briefly explain the different classes of cell surface receptors. [16]
8. Using a suitable example discuss the role of secondary messengers in signal trans-
duction. [16]
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Code No: 33111 Set No. 3
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. How can you determine whether a unicellular organism is a prokaryote or a eukary-
ote? Justify your statement with suitable illustrations. [16]
2. Discuss the importance of Carbon in a living cell. [16]
3. Cite the one unique function of each of the following: plasma membrane, nucleus,
nuclear envelope, mitochondrion, chloroplast, RER, SER, Golgi complex, secretory
vesicles, lysosome, peroxisomes, ribosomes, cytoskeleton, microtubules, microfila-
ments, intermediate filaments, extracellular matrix, cell wall. [16]
4. What are Lysosomal & Vacuolar membrane pumps? [16]
5. Write about the early experiments, which led to the discovery of cyclin dependent
kinases. [16]
6. Using suitable examples explain cytoplasmic determinants in cell differentiation.
[16]
7. Define a “receptor”. Discuss briefly the different types of receptors. [16]
8. Define signal transduction and explain it briefly. [16]
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Code No: 33111 Set No. 4
II B.Tech I Semester Supplimentary Examinations, May/Jun 2009
CELL BIOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆ ⋆ ⋆ ⋆ ⋆
1. Compare and contrast the properties and strategies of eukaryotic and prokaryotic
cells in terms of cell size, compartmentalization, nuclei, internal membranes, DNA
and cell specialization. [16]
2. Justify the statement “Plasma membrane acts as a semi-permeable membrane in
libing cells”. [16]
3. What is the function of Peroxisomes? Where are they present? [16]
4. Describe the process of receptor-mediated endocytosis with suitable illustrations.
[16]
5. Drawl and label the cell cycle and describe the events that occur during each
stage/phase of the cell cycle. [16]
6. Discuss the general characteristics of cell differentiation. [16]
7. What role does flagellar motion play in bacterial chemo taxis? [16]
8. Define signal transduction and explain it briefly. [16]
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